Faculty Rank: Associate Professor
Medical or Graduate Education:
Harvard Medical School
Neurological Institute of New York, Columbia University - Neurological Surgery
University of Chicago Medical Center - Spine Surgery
Spine surgery, minimally invasive
Clinical outcomes for spinal surgery
Development of evidence-based guidelines for spinal surgery
Development of new spinal surgical techniques and devices
Image-guided spinal surgery
Translational application of spinal biologics
Below is a list of scientific publications for which this practitioner was either the primary author or a contributor. Citations come from PubMed, a database of biomedical literature, life science journals and online books. PubMed is a service of the US Library of Medicine at the National Institutes of Health. Click on the title of the cited work for more information (this will take you directly to PubMed.gov). Listings go back five years.
Minimally invasive combined direct lateral and posterior transpedicular approach for 360° resection of a lumbar aneurysmal bone cyst with spinal stabilization. Tan LA, Kasliwal MK, O'Toole JE Spine J 2015 Oct 1 15(10):e37-8. Intramedullary Spinal Cord Tumors: Part I-Epidemiology, Pathophysiology, and Diagnosis. Samartzis D, Gillis CC, Shih P, O'Toole JE, Fessler RG Global Spine J 2015 Oct 5(5):425-35. Guest editorial: high impact spinal surgery articles. O'Toole JE Neurosurgery 2015 Mar 76 Suppl 1:S1-3. High Cervical Spinal Subdural Hemorrhage as a Harbinger of Craniocervical Arteriovenous Fistula - An Unusual Clinical Presentation. Kasliwal MK, Moftakhar R, O'Toole JE, Lopes DK Spine J 2015 Feb 25 :. Prion Protein Protects against Renal Ischemia/Reperfusion Injury. Zhang B, Cowden D, Zhang F, Yuan J, Siedlak S, Abouelsaad M, Zeng L, Zhou X, O'Toole J, Das AS, Kofskey D, Warren M, Bian Z, Cui Y, Tan T, Kresak A, Wyza RE, Petersen RB, Wang GX, Kong Q, Wang X, Sedor J, Zhu X, Zhu H, Zou WQ PLoS ONE 2015 10(9):e0136923. Correction: Prion Protein Protects against Renal Ischemia/Reperfusion Injury. Zhang B, Cowden D, Zhang F, Yuan J, Siedlak S, Abouelsaad M, Zeng L, Zhou X, O'Toole J, Das AS, Kofskey D, Warren M, Bian Z, Cui Y, Tan T, Kresak A, Wyza RE, Petersen RB, Wang GX, Kong Q, Wang X, Sedor J, Zhu X, Zhu H, Zou WQ PLoS ONE 2015 10(10):e0141025. Inverted Mercedes Benz Sign in Lumbar Spinal Subdural Hematoma. Kasliwal MK, Shannon LR, O'Toole JE, Byrne RW J Emerg Med 2014 Sep 30 :. Minimally invasive surgery for synchronous, same-level lumbar intradural-extramedullary neoplasm and acute disc herniation. Tan LA, Kasliwal MK, Wewel J, Fontes RB, O'Toole JE Neurosurg Focus 2014 Sep 37 Suppl 2:Video 16. Single-level anterior cervical discectomy and fusion versus minimally invasive posterior cervical foraminotomy for patients with cervical radiculopathy: a cost analysis. Mansfield HE, Canar WJ, Gerard CS, O'Toole JE Neurosurg Focus 2014 Nov 37(5):E9. Compressive radiculopathy due to delayed pseudomeningocele secondary to occult dural tear following tubular lumbar microdiscectomy. Tan LA, Kasliwal MK, O'Toole JE Neurol India 2014 May-Jun 62(3):318-20. Management of intended durotomy in minimally invasive intradural spine surgery. Tan LA, Takagi I, Straus D, O'Toole JE J Neurosurg Spine 2014 May 9 :1-7. Minimally Invasive Direct Lateral Approach to the Thoracolumbar Junction: Cadaveric Analysis and Case Illustrations. Straus D, Takagi I, O'Toole J J Neurol Surg A Cent Eur Neurosurg 2014 May 12 Tubular retractor selection in minimally invasive spinal tumor resection. Tan LA, O'Toole JE J Neurosurg Spine 2014 May 20(5):596-7; author reply 597-8. Intradural tumor recurrence after resection of extradural metastasis: a rare but potential complication of intraoperative durotomy. Kasliwal MK, Tan LA, O'Toole JE J Neurosurg Spine 2014 Jun 20(6):734-9. Rapidly progressive quadriparesis heralding disseminated coccidioidomycosis in an immunocompetent patient. Tan LA, Kasliwal MK, Nag S, O'Toole JE, Traynelis VC J Clin Neurosci 2014 Jun 21(6):1049-51. Extensive vertebral scalloping in a case of giant cystic spinal schwannoma: more than just a radiological diagnosis. Corley J, Kasliwal MK, O'Toole JE, Byrne RW J. Neurooncol. 2014 Jul 14 Disseminated spinal myxopapillary ependymoma in an adult at initial presentation: A case report and review of the literature. Straus D, Tan LA, Takagi I, O'Toole JE Br J Neurosurg 2014 Jan 24 Position statement on percutaneous vertebral augmentation: a consensus statement developed by the Society of Interventional Radiology (SIR), American Association of Neurological Surgeons (AANS) and the Congress of Neurological Surgeons (CNS), American College of Radiology (ACR), American Society of Neuroradiology (ASNR), American Society of Spine Radiology (ASSR), Canadian Interventional Radiology Association (CIRA), and the Society of NeuroInterventional Surgery (SNIS). Barr JD, Jensen ME, Hirsch JA, McGraw JK, Barr RM, Brook AL, Meyers PM, Munk PL, Murphy KJ, O'Toole JE, Rasmussen PA, Ryken TC, Sanelli PC, Schwartzberg MS, Seidenwurm D, Tutton SM, Zoarski GH, Kuo MD, Rose SC, Cardella JF J Vasc Interv Radiol 2014 Feb 25(2):171-81. Methadone-maintained patients in primary care have higher rates of chronic disease and multimorbidity, and use health services more intensively than matched controls. O'Toole J, Hambly R, Cox AM, O'Shea B, Darker C Eur J Gen Pract 2014 Dec 20(4):275-80. ACR Appropriateness Criteria Management of Vertebral Compression Fractures. McConnell CT, Wippold FJ, Ray CE, Weissman BN, Angevine PD, Fries IB, Holly LT, Kapoor BS, Lorenz JM, Luchs JS, O'Toole JE, Patel ND, Roth CJ, Rubin DA J Am Coll Radiol 2014 Aug 11(8):757-63. Current techniques in the management of cervical myelopathy and radiculopathy. Gerard CS, O'Toole JE Neurosurg. Clin. N. Am. 2014 Apr 25(2):261-70. The Technological Development of Minimally Invasive Spine Surgery. Snyder LA, O'Toole J, Eichholz KM, Perez-Cruet MJ, Fessler R Biomed Res Int 2014 2014:293582. Clinical experience using polyetheretherketone (PEEK) intervertebral structural cage for anterior cervical corpectomy and fusion. Kasliwal MK, O'Toole JE J Clin Neurosci 2013 Sep 6 Prevention of orthopaedic implant infection in patients undergoing dental procedures. Watters W 3rd, Rethman MP, Hanson NB, Abt E, Anderson PA, Carroll KC, Futrell HC, Garvin K, Glenn SO, Hellstein J, Hewlett A, Kolessar D, Moucha C, O'Donnell RJ, O'Toole JE, Osmon DR, Evans RP, Rinella A, Steinberg MJ, Goldberg M, Ristic H, Boyer K, et al. J Am Acad Orthop Surg. 2013 2013 Mar 21(3):180-9. doi: 10.5435/JAAOS-21-03-180. Minimally invasive treatment of spinal dural arteriovenous fistula with the use of intraoperative indocyanine green angiography. Fontes RB, Tan LA, O'Toole JE Neurosurg Focus 2013 Jul 35(2 Suppl):Video 5. Isolated spinal neurosarcoidosis: An enigmatic intramedullary spinal cord pathology-case report and review of the literature. Kasliwal MK, Harbhajanka A, Nag S, O'Toole JE J Craniovertebr Junction Spine 2013 Jul 4(2):76-81. Hyperbolic source location of crack related acoustic emission in bone. O'Toole J, Creedon L, Hession J, Muir G J Biomech Eng 2013 Jan 135(1):011006. Timing of Surgery after Cervical Spinal Cord Injury. O'Toole JE. World Neurosurg. 2013 2013 Feb 8. doi:pii: S1878-8750(13)00289-1. 10.1016/j.wneu.2013.02.024. [Epub ahead of print] No abstract available. The future of minimally invasive spine surgery. O'Toole JE Neurosurgery 2013 Aug 60 Suppl 1:13-9. A rare intramedullary spinal cord metastasis from uterine leiomyosarcoma. Tan LA, Kasliwal MK, Nag S, O'Toole JE. J Clin Neurosci. 2013 2013 Apr 13. doi:pii: S0967-5868(12)00537-1. 10.1016/j.jocn.2012.09.006. [Epub ahead of print] Minimally Invasive Thoracic Microendoscopic Diskectomy: Surgical Technique and Case Series. Smith JS, Eichholz KM, Shafizadeh S, Ogden AT, O'Toole JE, Fessler RG. World Neurosurg. 2012 2012 Oct 5. doi:pii: S1878-8750(12)01095-9. 10.1016/j.wneu.2012.05.031. [Epub ahead of print] Unilateral paramedian transpedicular approach for repair of anterior transdural spinal cord herniation: report of a case and literature review. Kasliwal MK, O'toole JE, Deutsch H. Asian Spine J. 2012 2012 Mar 6(1):55-9. doi: 10.4184/asj.2012.6.1.55. Epub 2012 Mar 9. Chordoma of the thoracic spine in an 89-year-old. Fontes R, O'Toole JE. Eur Spine J. 2012 2012 Jun 21 Suppl 4:S428-32. doi: 10.1007/s00586-011-1980-6. Epub 2011 Aug 25. Integrated intervertebral device for anterior cervical fusion: An initial experience. Kasliwal MK, O'toole JE J Craniovertebr Junction Spine 2012 7 3(2):52-57. Management of incidental durotomy in minimally invasive spine surgery. Ruban D, O'Toole JE. Neurosurg Focus. 2011 2011 Oct 31(4):E15. doi: 10.3171/2011.7.FOCUS11122. Unique radiologic feature of spinal plasmacytoma: mini-brain appearance. Kasliwal MK, O'Toole JE. Neurol India. 2011 2011 May-Jun 59(3):486-7. doi: 10.4103/0028-3886.82765. No abstract available. Vertebral compression fractures. O'Toole JE, Traynelis VC. J Neurosurg Spine. 2011 2011 May 14(5):555-9; discussion 559-60. doi: 10.3171/2010.10.SPINE10622. Epub 2011 Mar 4. No abstract available. A novel technique for temporary fixation during posterolateral thoracic corpectomy. Ruban D, O'Toole JE. J Spinal Disord Tech. 2011 2011 Dec 24(8):E66-70. doi: 10.1097/BSD.0b013e318227b549. Cadaveric evaluation of minimally invasive posterolateral thoracic corpectomy: a comparison of 3 approaches. Ogden AT, Eichholz K, O'toole J, Smith JS, Gala V, Voyadzis JM, Sugimoto K, Song J, Fessler RG. J Spinal Disord Tech. 2009 2009 Oct 22(7):524-9. doi: 10.1097/BSD.0b013e31818e5488. Surgical site infection rates after minimally invasive spinal surgery. O'Toole JE, Eichholz KM, Fessler RG. J Neurosurg Spine. 2009 2009 Oct 11(4):471-6. doi: 10.3171/2009.5.SPINE08633. Minimally invasive posterolateral thoracic corpectomy: cadaveric feasibility study and report of four clinical cases. Kim DH, O'Toole JE, Ogden AT, Eichholz KM, Song J, Christie SD, Fessler RG. Neurosurgery. 2009 2009 Apr 64(4):746-52; discussion 752-3. doi: 10.1227/01.NEU.0000340783.83964.27. Spinal epidural abscess associated with infliximab treatment for psoriatic arthritis. Case report. Smith AP, Musacchio MJ, O'Toole JE. J Neurosurg Spine. 2008 2008 Sep 9(3):261-4. Minimally invasive posterior osteotomies. Voyadzis JM, Gala VC, O'Toole JE, Eichholz KM, Fessler RG. Neurosurgery. 2008 2008 Sep 63(3 Suppl):204-10. doi: 10.1227/01.NEU.0000320430.37577.B7.
To watch a brief video of John O'Toole, MD, MS, click the play button at the lower left corner of the video frame below.
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The primary goals for much of what I do, in terms of the surgical treatment of spinal diseases, is trying to relieve pain and restore function. Most effective treatments that we can apply are geared towards helping people manage their pain and improve their pain levels, and ultimately improve their quality of life.
Surgery is invasive by definition. And the more we’ve been able to reduce the invasiveness of surgery, the better the outcomes have been for patients, the shorter the recovery times, less blood loss, and overall likely lower pain levels associated with the surgeries that we perform.
There’s a lot of misconceptions about spine surgery, and the effects on patients, and their long-term health and well-being. Patients who are properly selected for spinal surgery can do extraordinarily well with very high success rates for most of the disease we treat.
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