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Physician Profile


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Ece A. Mutlu, MD, MS, MBA

  • Gastroenterology
  • Internal Medicine
Board Certification:
  • Gastroenterology
  • Internal Medicine
Faculty Rank: Associate Professor
Medical or Graduate Education: Istanbul University Faculty of Medicine
Residency: Loyola University Medical Center - Internal Medicine
Fellowship: Loyola University Medical Center - Gastroenterology
  Rush University Medical Center - Gastroenterology
Clinical Expertise:
  • Argon plasma coagulation
  • Blood in stool
  • Capsule endoscopy
  • Chromoendoscopy
  • Colonoscopy
  • Crohn's disease
  • Endoscopic mucosal resection
  • Esophagogastroduodenoscopy (EGD)
  • Fistula
  • Microscopic colitis
  • Mucosectomy
  • Pouchitis
  • Radiation colitis
  • Ulcerative colitis
Research Interests:
  • Diet therapy in Inflammatory Bowel Disease
  • Role of microbiological flora on gastrointestinal illness
  • Role of nutrition in gastrointestinal disease
  • Complementary and alternative medicine for gastrointestinal disease
  • Antioxidant treatment of radiation proctitis
Languages Spoken:
  • Turkish
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Below is a list of scientific publications for which this practitioner was either the primary author or a contributor. Citations come from PubMed, a database of biomedical literature, life science journals and online books. PubMed is a service of the US Library of Medicine at the National Institutes of Health. Click on the title of the cited work for more information (this will take you directly to Listings go back five years.

  1. Colonic bacterial composition in Parkinson's disease.
    Keshavarzian A, Green SJ, Engen PA, Voigt RM, Naqib A, Forsyth CB, Mutlu E, Shannon KM
    Mov. Disord.
    2015 Sep
  2. Longitudinal Survey of Microbiota in Hospitalized Preterm Very Low Birth Weight Infants.
    Patel AL, Mutlu EA, Sun Y, Koenig L, Green S, Jakubowicz A, Mryan J, Engen P, Fogg L, Chen AL, Pombar X, Meier PP, Keshavarzian A
    J. Pediatr. Gastroenterol. Nutr.
    2015 Jul 29
  3. Disease-specific alterations in the enteric virome in inflammatory bowel disease.
    Norman JM, Handley SA, Baldridge MT, Droit L, Liu CY, Keller BC, Kambal A, Monaco CL, Zhao G, Fleshner P, Stappenbeck TS, McGovern DP, Keshavarzian A, Mutlu EA, Sauk J, Gevers D, Xavier RJ, Wang D, Parkes M, Virgin HW
    2015 Jan 29
  4. HIV-associated mucosal gene expression: region-specific alterations.
    Voigt RM, Keshavarzian A, Losurdo J, Swanson G, Siewe B, Forsyth CB, French AL, Demarais P, Engen P, Raeisi S, Mutlu E, Landay AL
    2015 Jan 14
  5. The Specific Carbohydrate Diet for Inflammatory Bowel Disease: A Case Series.
    Kakodkar S, Farooqui AJ, Mikolaitis SL, Mutlu EA
    J Acad Nutr Diet
    2015 Aug
  6. Classification methods for the analysis of LH-PCR data associated with inflammatory bowel disease patients.
    Wisittipanit N, Rangwala H, Sikaroodi M, Keshavarzian A, Mutlu EA, Gillevet P
    Int J Bioinform Res Appl
  7. Alcohol Induced Alterations to the Human Fecal VOC Metabolome.
    Couch RD, Dailey A, Zaidi F, Navarro K, Forsyth CB, Mutlu E, Engen PA, Keshavarzian A
    PLoS ONE
  8. Supplementation of Saturated Long-chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice.
    Chen P, Torralba M, Tan J, Embree M, Zengler K, Stärkel P, Pijkeren JP, DePew J, Loomba R, Ho SB, Bajaj JS, Mutlu EA, Keshavarzian A, Tsukamoto H, Nelson KE, Fouts DE, Schnabl B
    2014 Sep 16
  9. Hepatitis B vaccination in patients with inflammatory bowel disease.
    Ben Musa R, Gampa A, Basu S, Keshavarzian A, Swanson G, Brown M, Abraham R, Bruninga K, Losurdo J, DeMeo M, Mobarhan S, Shapiro D, Mutlu E
    World J. Gastroenterol.
    2014 Nov 7
  10. TNF inhibitors to treat ulcerative colitis in a metastatic breast cancer patient: a case report and literature review.
    Ben Musa R, Usha L, Hibbeln J, Mutlu EA
    World J. Gastroenterol.
    2014 May 21
  11. A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects.
    Mutlu EA, Keshavarzian A, Losurdo J, Swanson G, Siewe B, Forsyth C, French A, Demarais P, Sun Y, Koenig L, Cox S, Engen P, Chakradeo P, Abbasi R, Gorenz A, Burns C, Landay A
    PLoS Pathog.
    2014 Feb
  12. Risk factors for severe or fatal drug-induced liver injury from amoxicillin-clavulanic acid.
    Yazici C, Mutlu E, Bonkovsky HL, Russo MW
    Hepatol. Res.
    2014 Aug 28
  13. Circadian disorganization alters intestinal microbiota.
    Voigt RM, Forsyth CB, Green SJ, Mutlu E, Engen P, Vitaterna MH, Turek FW, Keshavarzian A
    PLoS ONE
  14. The approach to sample acquisition and its impact on the derived human fecal microbiome and VOC metabolome.
    Couch RD, Navarro K, Sikaroodi M, Gillevet P, Forsyth CB, Mutlu E, Engen PA, Keshavarzian A
    PLoS ONE
  15. Inpatient capsule endoscopy leads to frequent incomplete small bowel examinations.
    Yazici C, Losurdo J, Brown MD, Oosterveen S, Rahimi R, Keshavarzian A, Bozorgnia L, Mutlu E.
    World J Gastroenterol. 2012
    2012 Sep 28
    18(36):5051-7. doi: 10.3748/wjg.v18.i36.5051.
  16. Colonic microbiome is altered in alcoholism.
    Mutlu EA, Gillevet PM, Rangwala H, Sikaroodi M, Naqvi A, Engen PA, Kwasny M, Lau CK, Keshavarzian A.
    Am J Physiol Gastrointest Liver Physiol. 2012
    2012 May 1
    302(9):G966-78. doi: 10.1152/ajpgi.00380.2011. Epub 2012 Jan 12.
  17. Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease.
    Shannon KM, Keshavarzian A, Mutlu E, Dodiya HB, Daian D, Jaglin JA, Kordower JH.
    Mov Disord. 2012
    2012 May
    27(6):709-15. doi: 10.1002/mds.23838. Epub 2011 Jul 15.
  18. Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice.
    Mutlu EA, Engen PA, Soberanes S, Urich D, Forsyth CB, Nigdelioglu R, Chiarella SE, Radigan KA, Gonzalez A, Jakate S, Keshavarzian A, Budinger GR, Mutlu GM.
    Part Fibre Toxicol. 2011
    2011 Jun 9
    8:19. doi: 10.1186/1743-8977-8-19.
  19. Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms.
    Budinger GR, McKell JL, Urich D, Foiles N, Weiss I, Chiarella SE, Gonzalez A, Soberanes S, Ghio AJ, Nigdelioglu R, Mutlu EA, Radigan KA, Green D, Kwaan HC, Mutlu GM.
    PLoS One. 2011
    2011 Apr 11
    6(4):e18525. doi: 10.1371/journal.pone.0018525.
  20. Quantitative assessment of the human gut microbiome using multitag pyrosequencing.
    Gillevet P, Sikaroodi M, Keshavarzian A, Mutlu EA.
    Chem Biodivers. 2010
    2010 May
    7(5):1065-75. doi: 10.1002/cbdv.200900322.
  21. Sacral nerve stimulation for fecal incontinence: results of a 120-patient prospective multicenter study.
    Wexner SD, Coller JA, Devroede G, Hull T, McCallum R, Chan M, Ayscue JM, Shobeiri AS, Margolin D, England M, Kaufman H, Snape WJ, Mutlu E, Chua H, Pettit P, Nagle D, Madoff RD, Lerew DR, Mellgren A.
    Ann Surg. 2010
    2010 Mar
    251(3):441-9. doi: 10.1097/SLA.0b013e3181cf8ed0.
  22. Infection rates in a large investigational trial of sacral nerve stimulation for fecal incontinence.
    Wexner SD, Hull T, Edden Y, Coller JA, Devroede G, McCallum R, Chan M, Ayscue JM, Shobeiri AS, Margolin D, England M, Kaufman H, Snape WJ, Mutlu E, Chua H, Pettit P, Nagle D, Madoff RD, Lerew DR, Mellgren A.
    J Gastrointest Surg. 2010
    2010 Jul
    14(7):1081-9. doi: 10.1007/s11605-010-1177-z. Epub 2010 Mar 31.
  23. Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats.
    Mutlu E, Keshavarzian A, Engen P, Forsyth CB, Sikaroodi M, Gillevet P.
    Alcohol Clin Exp Res. 2009
    2009 Oct
    33(10):1836-46. doi: 10.1111/j.1530-0277.2009.01022.x. Epub 2009 Jul 23.
  24. Reconsidering the methodology of stress research in inflammatory bowel disease.
    Keefer L, Keshavarzian A, Mutlu E.
    J Crohns Colitis. 2008
    2008 Sep
    2(3):193-201. doi: 10.1016/j.crohns.2008.01.002. Epub 2008 Mar 10.
  25. To diet or not if you have inflammatory bowel disease.
    Mutlu EA, Gor N.
    Expert Rev Gastroenterol Hepatol. 2008
    2008 Oct
    2(5):613-6. doi: 10.1586/17474124.2.5.613. No abstract available.
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