Faculty Rank: Associate Professor
Medical or Graduate Education:
Istanbul University Faculty of Medicine
Loyola University Medical Center - Internal Medicine
Loyola University Medical Center - Gastroenterology
Rush University Medical Center - Gastroenterology
Argon plasma coagulation
Blood in stool
Endoscopic mucosal resection
Diet therapy in Inflammatory Bowel Disease
Role of microbiological flora on gastrointestinal illness
Role of nutrition in gastrointestinal disease
Complementary and alternative medicine for gastrointestinal disease
Antioxidant treatment of radiation proctitis
Below is a list of scientific publications for which this practitioner was either the primary author or a contributor. Citations come from PubMed, a database of biomedical literature, life science journals and online books. PubMed is a service of the US Library of Medicine at the National Institutes of Health. Click on the title of the cited work for more information (this will take you directly to PubMed.gov). Listings go back five years.
TNF inhibitors to treat ulcerative colitis in a metastatic breast cancer patient: a case report and literature review. Ben Musa R, Usha L, Hibbeln J, Mutlu EA World J. Gastroenterol. 2014 May 21 20(19):5912-7. A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects. Mutlu EA, Keshavarzian A, Losurdo J, Swanson G, Siewe B, Forsyth C, French A, Demarais P, Sun Y, Koenig L, Cox S, Engen P, Chakradeo P, Abbasi R, Gorenz A, Burns C, Landay A PLoS Pathog. 2014 Feb 10(2):e1003829. Circadian disorganization alters intestinal microbiota. Voigt RM, Forsyth CB, Green SJ, Mutlu E, Engen P, Vitaterna MH, Turek FW, Keshavarzian A PLoS ONE 2014 9(5):e97500. The approach to sample acquisition and its impact on the derived human fecal microbiome and VOC metabolome. Couch RD, Navarro K, Sikaroodi M, Gillevet P, Forsyth CB, Mutlu E, Engen PA, Keshavarzian A PLoS ONE 2013 8(11):e81163. Inpatient capsule endoscopy leads to frequent incomplete small bowel examinations. Yazici C, Losurdo J, Brown MD, Oosterveen S, Rahimi R, Keshavarzian A, Bozorgnia L, Mutlu E. World J Gastroenterol. 2012 2012 Sep 28 18(36):5051-7. doi: 10.3748/wjg.v18.i36.5051. Colonic microbiome is altered in alcoholism. Mutlu EA, Gillevet PM, Rangwala H, Sikaroodi M, Naqvi A, Engen PA, Kwasny M, Lau CK, Keshavarzian A. Am J Physiol Gastrointest Liver Physiol. 2012 2012 May 1 302(9):G966-78. doi: 10.1152/ajpgi.00380.2011. Epub 2012 Jan 12. Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease. Shannon KM, Keshavarzian A, Mutlu E, Dodiya HB, Daian D, Jaglin JA, Kordower JH. Mov Disord. 2012 2012 May 27(6):709-15. doi: 10.1002/mds.23838. Epub 2011 Jul 15. Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice. Mutlu EA, Engen PA, Soberanes S, Urich D, Forsyth CB, Nigdelioglu R, Chiarella SE, Radigan KA, Gonzalez A, Jakate S, Keshavarzian A, Budinger GR, Mutlu GM. Part Fibre Toxicol. 2011 2011 Jun 9 8:19. doi: 10.1186/1743-8977-8-19. Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms. Budinger GR, McKell JL, Urich D, Foiles N, Weiss I, Chiarella SE, Gonzalez A, Soberanes S, Ghio AJ, Nigdelioglu R, Mutlu EA, Radigan KA, Green D, Kwaan HC, Mutlu GM. PLoS One. 2011 2011 Apr 11 6(4):e18525. doi: 10.1371/journal.pone.0018525. Quantitative assessment of the human gut microbiome using multitag pyrosequencing. Gillevet P, Sikaroodi M, Keshavarzian A, Mutlu EA. Chem Biodivers. 2010 2010 May 7(5):1065-75. doi: 10.1002/cbdv.200900322. Sacral nerve stimulation for fecal incontinence: results of a 120-patient prospective multicenter study. Wexner SD, Coller JA, Devroede G, Hull T, McCallum R, Chan M, Ayscue JM, Shobeiri AS, Margolin D, England M, Kaufman H, Snape WJ, Mutlu E, Chua H, Pettit P, Nagle D, Madoff RD, Lerew DR, Mellgren A. Ann Surg. 2010 2010 Mar 251(3):441-9. doi: 10.1097/SLA.0b013e3181cf8ed0. Infection rates in a large investigational trial of sacral nerve stimulation for fecal incontinence. Wexner SD, Hull T, Edden Y, Coller JA, Devroede G, McCallum R, Chan M, Ayscue JM, Shobeiri AS, Margolin D, England M, Kaufman H, Snape WJ, Mutlu E, Chua H, Pettit P, Nagle D, Madoff RD, Lerew DR, Mellgren A. J Gastrointest Surg. 2010 2010 Jul 14(7):1081-9. doi: 10.1007/s11605-010-1177-z. Epub 2010 Mar 31. Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats. Mutlu E, Keshavarzian A, Engen P, Forsyth CB, Sikaroodi M, Gillevet P. Alcohol Clin Exp Res. 2009 2009 Oct 33(10):1836-46. doi: 10.1111/j.1530-0277.2009.01022.x. Epub 2009 Jul 23. Reconsidering the methodology of stress research in inflammatory bowel disease. Keefer L, Keshavarzian A, Mutlu E. J Crohns Colitis. 2008 2008 Sep 2(3):193-201. doi: 10.1016/j.crohns.2008.01.002. Epub 2008 Mar 10. To diet or not if you have inflammatory bowel disease. Mutlu EA, Gor N. Expert Rev Gastroenterol Hepatol. 2008 2008 Oct 2(5):613-6. doi: 10.1586/17474184.108.40.2063. No abstract available.
To watch a brief video of Ece A. Mutlu, MD, click the play button at the lower left corner of the video frame below.
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My philosophy as a doctor is to be an educator for my patients so that they can manage their disease as well as I can manage their disease. I am not with them 24/7, so patients need to take some active role in their health care.
If they are involved in the decision-making, then they tend to follow through with the recommendations that we give, and the outcome tends to be better.