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Faculty Rank: Professor
Medical or Graduate Education:
Rush Medical College
Rush University Medical Center - Internal Medicine
Rush University Medical Center - Infectious Disease
Bone and joint infections
University Infectious Diseases Academic Facility 600 S. Paulina St. Suite 140 Chicago, IL 60612 Phone: (312) 942-5865 Fax: (312) 942-8200
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Below is a list of scientific publications for which this practitioner was either the primary author or a contributor. Citations come from PubMed, a database of biomedical literature, life science journals and online books. PubMed is a service of the US Library of Medicine at the National Institutes of Health. Click on the title of the cited work for more information (this will take you directly to PubMed.gov). Listings go back five years.
Multicenter study of high-dose daptomycin for treatment of enterococcal infections. Casapao AM, Kullar R, Davis SL, Levine DP, Zhao JJ, Potoski BA, Goff DA, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ Antimicrob. Agents Chemother. 2013 Sep 57(9):4190-6. Should Draining Wounds and Sinuses Associated With Hip and Knee Arthroplasties Be Cultured? Tetreault MW, Wetters NG, Aggarwal VK, Moric M, Segreti J, Huddleston, Parvizi J, Della Valle CJ J Arthroplasty 2013 Sep 28(8 Suppl):133-6. A multicentre evaluation of the effectiveness and safety of high-dose daptomycin for the treatment of infective endocarditis. Kullar R, Casapao AM, Davis SL, Levine DP, Zhao JJ, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ J. Antimicrob. Chemother. 2013 Dec 68(12):2921-6. Challenges in Assessing Microbial Susceptibility and Predicting Clinical Response to Newer-Generation Fluoroquinolones. Segreti J, Jones RN, Bertino JS. J Ocul Pharmacol Ther. 2011 Oct 14 Consensus Conference on Prevention of Central Line-Associated Bloodstream Infections: 2009 Segreti J, Garcia-Houchins S, Gorski L, Moureau N, Shomo J, Zack J, Stachnik J, Tanzi M, Moody ML J Infus Nurs 2011 March/April 34(2):126-133 High-dose daptomycin for treatment of complicated gram-positive infections: a large, multicenter, retrospective study. Kullar R, Davis SL, Levine DP, Zhao JJ, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ. Pharmacotherapy. 2011 Jun 31(6):527-36. American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis of periprosthetic joint infections of the hip and knee. Della Valle C, Parvizi J, Bauer TW, DiCesare PE, Evans RP, Segreti J, Spangehl M, Watters WC 3rd, Keith M, Turkelson CM, Wies JL, Sluka P, Hitchcock K; American Academy of Orthopaedic Surgeons. J Bone Joint Surg Am. 2011 Jul 20 93(14):1355-7 Comparison of outcomes from daptomycin or linezolid treatment for vancomycin-resistant enterococcal bloodstream infection: A retrospective, multicenter, cohort study Crank CW, Scheetz MH, Brielmaier B, Rose WE, Patel GP, Ritchie DJ, Segreti J Clin Ther 2010 Sep 32(10):1713-9 Microbiologic and clinical epidemiologic characteristics of the Chicago subset of a multistate outbreak of Serratia marcescens bacteremia Sikka MK, Hayden MK, Pur S, Segreti J, Harris AA, Weinstein RA, Trenholme G Infect Control Hosp Epidemiol 2010 Nov 31(11):1191-3 Osteomyelitis Chihara S, Segreti J Dis Mon 2010 Jan 56(1):5-31 Diagnosis of periprosthetic joint infections of the hip and knee Della Valle C, Parvizi J, Bauer TW, Dicesare PE, Evans RP, Segreti J, Spangehl M, Watters WC 3rd, Keith M, Turkelson CM, Wies JL, Sluka P, Hitchcock K J Am Acad Orthop Surg 2010 Dec 18(12):760-70 Review of question and answer session Segreti J Int J Antimicrob Agents 2009 Jul 34 Suppl 1:S36-8 Empirical therapy for serious Gram-positive infections: making the right choice Segreti J Clin Microbiol Infect 2009 Dec 15 Suppl 6:5-10 University HealthSystem Consortium quality performance benchmarking study of the insertion and care of central venous catheters Harting BP, Talbot TR, Dellit TH, Hebden J, Cuny J, Greene WH, Segreti J Infect Control Hosp Epidemiol 2008 May 29(5):440-2 Is it bacterial or viral? Criteria for distinguishing bacterial and viral infections Benninger M, Segreti J J Fam Pract 2008 Feb 57(2 Suppl Managing):S5-11 Health care-associated pneumonia (HCAP): a critical appraisal to improve identification, management, and outcomes--proceedings of the HCAP Summit Kollef MH, Morrow LE, Baughman RP, Craven DE, McGowan JE Jr, Micek ST, Niederman MS, Ost D, Paterson DL, Segreti J Clin Infect Dis 2008 Apr 15 46 Suppl 4:S296-334; quiz 335-8 Antibiotic therapy of methicillin-resistant Staphylococcus aureus in critical care Tverdek FP, Crank CW, Segreti J Crit Care Clin 2008 Apr 24(2):249-60, vii-viii
To watch a brief video of John Segreti, MD, click the play button at the lower left corner of the video frame below.
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One of the biggest developments in the field of infectious diseases is the realization that not everyone needs to be on antibiotics forever. Whether it’s bacteria on the skin, bacteria in the throat, bacteria in the GI tract, once you give an antibiotic that can disrupt that normal flora, you could actually be causing more problems.
Many of the patients that I see on an outpatient basis are for second opinions — people that have been taken care of by their primary care doctor or another infectious disease person. I am trying to educate them about what’s going on, make them comfortable with their referring doctor. And, I try to do this not only for the patient, but also for their family.