Faculty Rank: Professor
Medical or Graduate Education:
Rush Medical College
Rush University Medical Center - Internal Medicine
Rush University Medical Center - Infectious Disease
Below is a list of scientific publications for which this practitioner was either the primary author or a contributor. Citations come from PubMed, a database of biomedical literature, life science journals and online books. PubMed is a service of the US Library of Medicine at the National Institutes of Health. Click on the title of the cited work for more information (this will take you directly to PubMed.gov). Listings go back five years.
Treatment Outcomes with Cefazolin versus Oxacillin for Deep-Seated Methicillin-Susceptible Staphylococcus aureus Bloodstream Infections. Rao SN, Rhodes NJ, Lee BJ, Scheetz MH, Hanson AP, Segreti J, Crank CW, Wang SK Antimicrob. Agents Chemother. 2015 Sep 59(9):5232-8. Chicago Ebola Response Network (CERN): A Citywide Cross-hospital Collaborative for Infectious Disease Preparedness. Lateef O, Hota B, Landon E, Kociolek LK, Morita J, Black S, Noskin G, Kelleher M, Curell K, Galat A, Ansell D, Segreti J, Weber SG Clin. Infect. Dis. 2015 Jun 29 :. Pseudo-outbreak of Mycobacterium gordonae Following the Opening of a Newly Constructed Hospital at a Chicago Medical Center. Prabaker K, Muthiah C, Hayden MK, Weinstein RA, Cheerala J, L Scorza M, Segreti J, Lavin MA, Schmitt BA, Welbel SF, Beavis KG, Trenholme GM Infect Control Hosp Epidemiol 2015 Feb 36(2):198-203. Conventional diagnostic challenges in periprosthetic joint infection. Nodzo SR, Bauer T, Pottinger PS, Garrigues GE, Bedair H, Deirmengian CA, Segreti J, Blount KJ, Omar IM, Parvizi J J Am Acad Orthop Surg 2015 Apr 23 Suppl:S18-25. In memoriam: John P. Quinn, MD. Perez F, Arias CA, Bush K, Drusano GL, Lolans K, Munoz-Price LS, Nicolau DP, Queenan AM, Rice LB, Segreti J, Shlaes DM, Weinstein RA, Bonomo RA Clin. Infect. Dis. 2014 Mar 58(5):748-50. Oral antibiotic therapy. O'Toole P, Osmon D, Soriano A, Berdal JE, Bostrum M, Franco-Cendejas R, Huang D, Nelson C, Nishisaka F, Roslund B, Salgado CD, Sawyer R, Segreti J, Senneville E, Zhang XL J. Orthop. Res. 2014 Jan 32 Suppl 1:S152-7. Oral antibiotic therapy. O'Toole P, Osmon D, Soriano A, Berdal JE, Bostrum M, Franco-Cendejas R, Huang D, Nelson C, Nishisaka F, Salgado CD, Sawyer R, Segreti J, Senneville E, Zhang XL J Arthroplasty 2014 Feb 29(2 Suppl):115-8. Multicenter study of high-dose daptomycin for treatment of enterococcal infections. Casapao AM, Kullar R, Davis SL, Levine DP, Zhao JJ, Potoski BA, Goff DA, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ Antimicrob. Agents Chemother. 2013 Sep 57(9):4190-6. Should Draining Wounds and Sinuses Associated With Hip and Knee Arthroplasties Be Cultured? Tetreault MW, Wetters NG, Aggarwal VK, Moric M, Segreti J, Huddleston, Parvizi J, Della Valle CJ J Arthroplasty 2013 Jul 29 A multicentre evaluation of the effectiveness and safety of high-dose daptomycin for the treatment of infective endocarditis. Kullar R, Casapao AM, Davis SL, Levine DP, Zhao JJ, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ J. Antimicrob. Chemother. 2013 Aug 8 Challenges in assessing microbial susceptibility and predicting clinical response to newer-generation fluoroquinolones. Segreti J, Jones RN, Bertino JS Jr. J Ocul Pharmacol Ther. 2012 2012 Feb 28(1):3-11. doi: 10.1089/jop.2011.0072. Epub 2011 Oct 14. Review. Consensus conference on prevention of central line-associated bloodstream infections: 2009. Segreti J, Garcia-Houchins S, Gorski L, Moureau N, Shomo J, Zack J, Stachnik J, Tanzi M, Moody ML. J Infus Nurs. 2011 2011 Mar-Apr 34(2):126-33. doi: 10.1097/NAN.0b013e31820b8a3e. High-dose daptomycin for treatment of complicated gram-positive infections: a large, multicenter, retrospective study. Kullar R, Davis SL, Levine DP, Zhao JJ, Crank CW, Segreti J, Sakoulas G, Cosgrove SE, Rybak MJ. Pharmacotherapy. 2011 2011 Jun 31(6):527-36. doi: 10.1592/phco.31.6.527. American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis of periprosthetic joint infections of the hip and knee. Della Valle C, Parvizi J, Bauer TW, DiCesare PE, Evans RP, Segreti J, Spangehl M, Watters WC 3rd, Keith M, Turkelson CM, Wies JL, Sluka P, Hitchcock K; American Academy of Orthopaedic Surgeons. J Bone Joint Surg Am. 2011 2011 Jul 20 93(14):1355-7. doi: 10.2106/JBJS.9314ebo. No abstract available. Comparison of outcomes from daptomycin or linezolid treatment for vancomycin-resistant enterococcal bloodstream infection: A retrospective, multicenter, cohort study. Crank CW, Scheetz MH, Brielmaier B, Rose WE, Patel GP, Ritchie DJ, Segreti J. Clin Ther. 2010 2010 Sep 32(10):1713-9. doi: 10.1016/j.clinthera.2010.09.008. Microbiologic and clinical epidemiologic characteristics of the Chicago subset of a multistate outbreak of Serratia marcescens bacteremia. Sikka MK, Hayden MK, Pur S, Segreti J, Harris AA, Weinstein RA, Trenholme G. Infect Control Hosp Epidemiol. 2010 2010 Nov 31(11):1191-3. doi: 10.1086/657074. Osteomyelitis. Chihara S, Segreti J. Dis Mon. 2010 2010 Jan 56(1):5-31. doi: 10.1016/j.disamonth.2009.07.001. Review. No abstract available. Diagnosis of periprosthetic joint infections of the hip and knee. Della Valle C, Parvizi J, Bauer TW, Dicesare PE, Evans RP, Segreti J, Spangehl M, Watters WC 3rd, Keith M, Turkelson CM, Wies JL, Sluka P, Hitchcock K; American Academy of Orthopaedic Surgeons. J Am Acad Orthop Surg. 2010 2010 Dec 18(12):760-70. Review of question and answer session. Segreti J. Int J Antimicrob Agents. 2009 2009 Jul 34 Suppl 1:S36-8. doi: 10.1016/S0924-8579(09)70548-5. Review. Empirical therapy for serious Gram-positive infections: making the right choice Segreti J Clin Microbiol Infect 2009 Dec 15 Suppl 6:5-10 University HealthSystem Consortium quality performance benchmarking study of the insertion and care of central venous catheters. Harting BP, Talbot TR, Dellit TH, Hebden J, Cuny J, Greene WH, Segreti J. Infect Control Hosp Epidemiol. 2008 2008 May 29(5):440-2. doi: 10.1086/587716. Is it bacterial or viral? Criteria for distinguishing bacterial and viral infections. Benninger M, Segreti J. J Fam Pract. 2008 2008 Feb 57(2 Suppl Managing):S5-11. Review. No abstract available. Health care-associated pneumonia (HCAP): a critical appraisal to improve identification, management, and outcomes--proceedings of the HCAP Summit. Kollef MH, Morrow LE, Baughman RP, Craven DE, McGowan JE Jr, Micek ST, Niederman MS, Ost D, Paterson DL, Segreti J. Clin Infect Dis. 2008 2008 Apr 15 46 Suppl 4:S296-334; quiz 335-8. doi: 10.1086/526355. Antibiotic therapy of methicillin-resistant Staphylococcus aureus in critical care. Tverdek FP, Crank CW, Segreti J. Crit Care Clin. 2008 2008 Apr 24(2):249-60, vii-viii. doi: 10.1016/j.ccc.2007.12.013.
To watch a brief video of John Segreti, MD, click the play button at the lower left corner of the video frame below.
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One of the biggest developments in the field of infectious diseases is the realization that not everyone needs to be on antibiotics forever. Whether it’s bacteria on the skin, bacteria in the throat, bacteria in the GI tract, once you give an antibiotic that can disrupt that normal flora, you could actually be causing more problems.
Many of the patients that I see on an outpatient basis are for second opinions — people that have been taken care of by their primary care doctor or another infectious disease person. I am trying to educate them about what’s going on, make them comfortable with their referring doctor. And, I try to do this not only for the patient, but also for their family.