Faculty Rank: Associate Professor
Medical or Graduate Education:
Chicago Medical School
Henry Ford Hospital - Neurology
Rush Alzheimer's Disease Center; Rush Institute for Healthy Aging - Aging and Neurodegenerative Disorders
Mild cognitive impairment (MCI)
Biomarkers for Alzheimer's disease
Community-based participatory research
Health disparities and health literacy
Links between heart health and cognitive function in women
Minority recruitment and engagement in clinical trials
Below is a list of scientific publications for which this practitioner was either the primary author or a contributor. Citations come from PubMed, a database of biomedical literature, life science journals and online books. PubMed is a service of the US Library of Medicine at the National Institutes of Health. Click on the title of the cited work for more information (this will take you directly to PubMed.gov). Listings go back five years.
Racial Differences in Cognitive Function and Risk of Incident Stroke. Rajan KB, Schneider JA, Aggarwal NT, Wilson RS, Everson-Rose SA, Evans DA J Stroke Cerebrovasc Dis 2015 Sep 16 :. MIND diet slows cognitive decline with aging. Morris MC, Tangney CC, Wang Y, Sacks FM, Barnes LL, Bennett DA, Aggarwal NT Alzheimers Dement 2015 Sep 11(9):1015-22. Multi-Ethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI. Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, de Andrade M, Atkinson EJ, Beekman M, Beiser AS, Blanton SH, Boerwinkle E, Brickman AM, Bryan RN, Chauhan G, Chen CP, Chouraki V, de Craen AJ, Crivello F, Deary IJ, Deelen J, De Jager PL, Dufouil C, Elkind MS, Evans DA, Freudenberger P, Gottesman RF, Guðnason V, Habes M, Heckbert SR, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas CA, Knopman DS, Lewis CE, Liao J, Liewald DC, Luciano M, van der Lugt A, Martinez OO, Mayeux R, Mazoyer B, Nalls MA, Nauck M, Niessen WJ, Oostra BA, Psaty BM, Rice KM, Rotter JI, von Sarnowski B, Schmidt H, Schreiner PJ, Schuur M, Sidney SS, Sigurdsson S, Slagboom PE, Stott DJ, van Swieten JC, Teumer A, Töglhofer AM, Traylor M, Trompet S, Turner ST, Tzourio C, Uh HW, Uitterlinden AG, Vernooij MW, Wang JJ, Wong TY, Wardlaw JM, Windham BG, Wittfeld K, Wolf C, Wright CB, Yang Q, Zhao W, Zijdenbos A, Jukema JW, Sacco RL, Kardia SL, Amouyel P, Mosley TH, Longstreth WT, DeCarli CC, van Duijn CM, Schmidt R, Launer LJ, Grabe HJ, Seshadri SS, Ikram MA, Fornage M Circ Cardiovasc Genet 2015 Feb 7 :. From Neurodegeneration to Brain Health: An Integrated Approach. Petersen RB, Lissemore FM, Appleby B, Aggarwal N, Boyatzis R, Casadesus G, Cummings J, Jack A, Perry G, Safar J, Sajatovic M, Surewicz W, Wang Y, Whitehouse P, Lerner A J. Alzheimers Dis. 2015 Feb 26 :. MIND diet associated with reduced incidence of Alzheimer's disease. Morris MC, Tangney CC, Wang Y, Sacks FM, Bennett DA, Aggarwal NT Alzheimers Dement 2015 Feb 11 :. Mixed pathology is more likely in black than white decedents with Alzheimer dementia. Barnes LL, Leurgans S, Aggarwal NT, Shah RC, Arvanitakis Z, James BD, Buchman AS, Bennett DA, Schneider JA Neurology 2015 Aug 11 85(6):528-34. Social Determinants, Race, and Brain Health Outcomes: Findings from the Chicago Health and Aging Project. Aggarwal NT, Everson-Rose SA, Evans DA Curr Alzheimer Res 2015 12(7):622-31. Association of cognitive functioning, incident stroke, and mortality in older adults. Rajan KB, Aggarwal NT, Wilson RS, Everson-Rose SA, Evans DA Stroke 2014 Sep 45(9):2563-7. Perceived stress and change in cognitive function among adults 65 years and older. Aggarwal NT, Wilson RS, Beck TL, Rajan KB, Mendes de Leon CF, Evans DA, Everson-Rose SA Psychosom Med 2014 Jan 76(1):80-5. Perceived Stress Is Associated With Subclinical Cerebrovascular Disease in Older Adults. Aggarwal NT, Clark CJ, Beck TL, Mendes de Leon CF, Decarli C, Evans DA, Everson Rose SA. Am J Geriatr Psychiatry. 2013 2013 Jan 9. doi:pii: S1064-7481(12)00004-8. 10.1016/j.jagp.2012.06.001. [Epub ahead of print] Antemortem amyloid imaging and Î²-amyloid pathology in a case with dementia with Lewy bodies. Kantarci K, Yang C, Schneider JA, Senjem ML, Reyes DA, Lowe VJ, Barnes LL, Aggarwal NT, Bennett DA, Smith GE, Petersen RC, Jack CR Jr, Boeve BF. Neurobiol Aging. 2012 2012 May 33(5):878-85. doi: 10.1016/j.neurobiolaging.2010.08.007. Epub 2010 Oct 18. The Minority Aging Research Study: ongoing efforts to obtain brain donation in African Americans without dementia. Barnes LL, Shah RC, Aggarwal NT, Bennett DA, Schneider JA. Curr Alzheimer Res. 2012 2012 Jul 9(6):734-45. Accounting for bias due to selective attrition: the example of smoking and cognitive decline. Weuve J, Tchetgen Tchetgen EJ, Glymour MM, Beck TL, Aggarwal NT, Wilson RS, Evans DA, Mendes de Leon CF. Epidemiology. 2012 2012 Jan 23(1):119-28. doi: 10.1097/EDE.0b013e318230e861. Psychosocial Distress and Stroke Risk in Older Adults. Henderson KM, Clark CJ, Lewis TT, Aggarwal NT, Beck T, Guo H, Lunos S, Brearley A, de Leon CF, Evans DA, Everson-Rose SA. Stroke. 2012 2012 Dec 13. [Epub ahead of print] Characteristics of MR infarcts associated with dementia and cognitive function in the elderly. Aggarwal NT, Schneider JA, Wilson RS, Beck TL, Evans DA, Carli CD. Neuroepidemiology. 2012 2012 38(1):41-7. doi: 10.1159/000334438. Epub 2011 Dec 17. Trends in Alzheimer's disease and dementia in the asian-pacific region. Aggarwal NT, Tripathi M, Dodge HH, Alladi S, Anstey KJ. Int J Alzheimers Dis. 2012 2012 2012:171327. doi: 10.1155/2012/171327. Epub 2012 Dec 9. No abstract available. Neighborhood cohesion is associated with reduced risk of stroke mortality. Clark CJ, Guo H, Lunos S, Aggarwal NT, Beck T, Evans DA, Mendes de Leon C, Everson-Rose SA. Stroke. 2011 2011 May 42(5):1212-7. doi: 10.1161/STROKEAHA.110.609164. Epub 2011 Apr 14. Uncovering the genetic architecture of white matter disease. Aggarwal NT, De Jager PL. Ann Neurol. 2011 2011 Jun 69(6):907-8. doi: 10.1002/ana.22460. No abstract available. Cognitive activity and the cognitive morbidity of Alzheimer disease Wilson RS, Barnes LL, Aggarwal NT, Boyle PA, Hebert LE, Mendes de Leon CF, Evans DA Neurology 2010 Sep 14 75(11):990-6 Cognitive decline in incident Alzheimer disease in a community population Wilson RS, Aggarwal NT, Barnes LL, Mendes de Leon CF, Hebert LE, Evans DA Neurology 2010 Mar 23 74(12):951-5 Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility. Zuvich RL, McCauley JL, Oksenberg JR, Sawcer SJ, De Jager PL; International Multiple Sclerosis Genetics Consortium, Aubin C, Cross AH, Piccio L, Aggarwal NT, Evans D, Hafler DA, Compston A, Hauser SL, Pericak-Vance MA, Haines JL. Hum Genet. 2010 2010 Mar 127(5):525-35. doi: 10.1007/s00439-010-0789-4. Epub 2010 Jan 30. The association of magnetic resonance imaging measures with cognitive function in a biracial population sample. Aggarwal NT, Wilson RS, Bienias JL, De Jager PL, Bennett DA, Evans DA, DeCarli C. Arch Neurol. 2010 2010 Apr 67(4):475-82. doi: 10.1001/archneurol.2010.42. A battery of tests for assessing cognitive function in older Latino persons. Krueger KR, Wilson RS, Bennett DA, Aggarwal NT. Alzheimer Dis Assoc Disord. 2009 2009 Oct-Dec 23(4):384-8. doi: 10.1097/WAD.0b013e31819e0bfc. Biracial population study of mortality in mild cognitive impairment and Alzheimer disease. Wilson RS, Aggarwal NT, Barnes LL, Bienias JL, Mendes de Leon CF, Evans DA. Arch Neurol. 2009 2009 Jun 66(6):767-72. doi: 10.1001/archneurol.2009.80. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S; International MS Genetics Consortium, Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, et al. Nat Genet. 2009 2009 Jul 41(7):776-82. doi: 10.1038/ng.401. Epub 2009 Jun 14. The neuropathology of older persons with and without dementia from community versus clinic cohorts. Schneider JA, Aggarwal NT, Barnes L, Boyle P, Bennett DA. J Alzheimers Dis. 2009 2009 18(3):691-701. doi: 10.3233/JAD-2009-1227. Use of home-based formal services by adult day care clients with Alzheimer's disease. Skarupski KA, McCann JJ, Bienias JL, Wolinsky FD, Aggarwal NT, Evans DA. Home Health Care Serv Q. 2008 27(3):217-39.
To watch a brief video of Neelum T. Aggarwal, MD, click the play button at the lower left corner of the video frame below.
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I often say to people, especially when I’m diagnosing Alzheimer’s, “I don’t really want to talk about what you can’t do. Let’s talk about what you still can do, and how we can keep you doing what you can do.” And I think for many people they understand that, and they feel a little bit more comfortable. And that’s setting, “Ok. We’re going to maintain where I’m at right now.” And we’re going to do everything we can to achieve that goal.
Our population is aging rapidly. We know that. And it’s going to continue to do that. And as it does, we are seeing now people who make it to the age of 85 with no cognitive issues, and they live another 10 years doing very, very well. So these people are called the super-agers. And we’re trying to understand what is it about them that allows them to live such vibrant lives cognitively, and also with really good mobility and physical functioning.
I always stress with all of my patients — whether or not they have Alzheimer’s or not — is prevention. We are now looking at cardiovascular risk factors. How do they somehow either maybe bring on the disease earlier or set a person up, if you will, for having issues that may be related that, down the road, could lead to the disease.