Not Remembering, and Not Knowing ItPeople who will develop dementia may begin to lose awareness of their memory problems two to three years before the actual onset of the disease, according to a new study by researchers at Rush.
Below is a list of scientific publications for which this practitioner was either the primary author or a contributor. Citations come from PubMed, a database of biomedical literature, life science journals and online books. PubMed is a service of the US Library of Medicine at the National Institutes of Health. Click on the title of the cited work for more information (this will take you directly to PubMed.gov). Listings go back five years.
Multi-Ethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI. Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, de Andrade M, Atkinson EJ, Beekman M, Beiser AS, Blanton SH, Boerwinkle E, Brickman AM, Bryan RN, Chauhan G, Chen CP, Chouraki V, de Craen AJ, Crivello F, Deary IJ, Deelen J, De Jager PL, Dufouil C, Elkind MS, Evans DA, Freudenberger P, Gottesman RF, Guðnason V, Habes M, Heckbert SR, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas CA, Knopman DS, Lewis CE, Liao J, Liewald DC, Luciano M, van der Lugt A, Martinez OO, Mayeux R, Mazoyer B, Nalls MA, Nauck M, Niessen WJ, Oostra BA, Psaty BM, Rice KM, Rotter JI, von Sarnowski B, Schmidt H, Schreiner PJ, Schuur M, Sidney SS, Sigurdsson S, Slagboom PE, Stott DJ, van Swieten JC, Teumer A, Töglhofer AM, Traylor M, Trompet S, Turner ST, Tzourio C, Uh HW, Uitterlinden AG, Vernooij MW, Wang JJ, Wong TY, Wardlaw JM, Windham BG, Wittfeld K, Wolf C, Wright CB, Yang Q, Zhao W, Zijdenbos A, Jukema JW, Sacco RL, Kardia SL, Amouyel P, Mosley TH, Longstreth WT, DeCarli CC, van Duijn CM, Schmidt R, Launer LJ, Grabe HJ, Seshadri SS, Ikram MA, Fornage M Circ Cardiovasc Genet 2015 Feb 7 :.
I often say to people, especially when I’m diagnosing Alzheimer’s, “I don’t really want to talk about what you can’t do. Let’s talk about what you still can do, and how we can keep you doing what you can do.” And I think for many people they understand that, and they feel a little bit more comfortable. And that’s setting, “Ok. We’re going to maintain where I’m at right now.” And we’re going to do everything we can to achieve that goal.
Our population is aging rapidly. We know that. And it’s going to continue to do that. And as it does, we are seeing now people who make it to the age of 85 with no cognitive issues, and they live another 10 years doing very, very well. So these people are called the super-agers. And we’re trying to understand what is it about them that allows them to live such vibrant lives cognitively, and also with really good mobility and physical functioning.
I always stress with all of my patients — whether or not they have Alzheimer’s or not — is prevention. We are now looking at cardiovascular risk factors. How do they somehow either maybe bring on the disease earlier or set a person up, if you will, for having issues that may be related that, down the road, could lead to the disease.